Publicaciones científicas y casos clínicos

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The CyberKnife® Robotic Radiosurgery System in 2010

The CyberKnife in Clinical Use: Current Roles, Future Expectations

Stereotactic body radiotherapy for localized prostate cancer: disease control and quality of life at 6 years

In this large series with long-term follow-up, we found excellent biochemical control rates and low and acceptable toxicity, outcomes consistent with those reported for from high dose rate brachytherapy (HDR BT). Provided that measures are taken to account for prostate motion, SBRT’s distinct advantages over HDR BT.

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Stereotactic body Radiotherapy as monotherapy or post–external beam radiotherapy boost for prostate cancer

Early results with SBRT monotherapy and post-EBRT boost for PCa demonstrate acceptable PSA response and minimal toxicity. PSA nadir with SBRT boost appears comparable to those achieved with HDR brachytherapy boost.

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Stereotactic body radiotherapy and gemcitabine for locally advanced pancreatic cancer

Hypofractionated SBRT can be delivered quickly and effectively in patients with nonmetastatic, locally advanced, unresectable pancreatic cancer with acceptable side effects and minimal interference with gemcitabine chemotherapy.

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Comparison of planned dose distributions calculated by Monte Carlo and ray-trace algorithms for the treatment of lung tumors with CyberKnife

We establish that changing the treatment plan calculation algorithm from EPL to MC can produce large differences in target and critical organs’ dose coverage. The observed discrepancies are larger for plans using smaller collimator sizes and have strong dependency on the anatomical relationship of target-critical structures.

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Application of Robotic Stereotactic Radiotherapy to Peripheral Stage I Non-small Cell Lung Cancer with Curative Intent

In this small cohort of patients with stage I peripheral NSCLC, robotic stereotactic radiotherapy seems to be a safe and obviously superior alternative to conventionally fractionated radiotherapy, with results that may be approaching those obtained with lobectomy without the associated morbidity.

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Image-Guided Robotic Stereotactic Radiation Therapy with Fiducial-Free Tumor Tracking for Lung Cancer

Lung SBRT with fiducial-free tumor tracking is both feasible and effective. Local control rate is similar to what so far has been reported in other studies that have used markers for tumor tracking. Toxicity was lower as there was no fiducial implantation, thereby preventing cases of pneumothorax normally associated with this procedure.

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Cyberknife Stereotactic Body Radiation Therapy for Nonresectable Tumors of the Liver: Preliminary Results

CyberKnife radiosurgery is a safe and effective local treatment option for unresectable primary and secondary liver tumors. In the multidisciplinary management of malignant maladies of the liver, SBRT adds to our armamentarium of local treatment modalities as complementary or salvage therapy.

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